SGL — 001 / INTRANASAL

Signal.

A biologic that signals the brain to repair itself — backed by a clinical network and a closed-loop AI that reads your baseline back to you.

CLINICAL NETWORK · FLORIDA ROLLOUTREQUEST ACCESS →
5×10⁹
Target dose (in development)
Multiple
Metered doses / bottle
AI
Closed-loop AI on every baseline
Signal intranasal exosome spray bottle
10 mL · METERED SPRAY
§ 01 — The Clinical Network

One network. Every clinic in the loop.

Signal is delivered through a network of physician-led clinics, connected by a closed-loop AI. Every baseline, every reading, and every protocol update flows through the same loop — so each clinic practices with the knowledge of the whole network.

Physician oversightIn every clinic
Closed-loop AIOn every baseline
Shared protocolAcross the network
Initial rolloutFlorida — limited cohort
Now onboardingLongevity · Neurology · Regenerative
Request clinic access →LICENSED PHYSICIANS · IN-CLINIC DELIVERY
A network of clinics connected through a central closed-loop AI
CLINICS → CLOSED-LOOP AI → CLINICS
§ 02 — Thesis

Your brain knows how to repair itself. It just lost the signal.

§ 03 — The bottle

One bottle. Multiple metered doses.
Nose to brain.

Format10 mL metered spray
Target dose (in development)5×10⁹ particles / 100 µL
DeliveryNose-to-brain, bypasses BBB
Exosomes traveling from the nasal cavity into the brain
NOSE → OLFACTORY → BRAIN
§ 04 — Mechanism

The BBB doesn't apply here.

Signal exosomes cross the cribriform plate directly. No injection. No infusion. Ninety seconds, in clinic.

Read the full dossier →
§ 05 — Baseline your signal

Where is your signal today?

A 90-second baseline of six cognitive markers — and the clinical network's closed-loop AI reads your results back in plain language.

Take the Mind Diagnostic →
SIGNAL INDEX · SAMPLE
Cognitive clarity62/100
Focus & attention54/100
Working memory68/100
Sleep quality47/100
Mood regulation71/100
Drive & motivation58/100
§ 06 — Closed-loop AI

Answers, on the record.

A clinical network — physician oversight with a closed-loop AI trained on Signal's science, protocol, and physician program. Ask about the mechanism, the dose, or what your Mind Diagnostic reading means.

Talk to the clinical network →
CLINICAL NETWORK · CLOSED-LOOP AI
How does the spray reach the brain?
Through the olfactory and trigeminal pathways — nose to brain, bypassing the blood-brain barrier.
What did my Mind Diagnostic show?
A plain-language reading of your baseline — illustrative only, never a diagnosis.

NOT MEDICAL ADVICE · HISTORY STAYS IN YOUR BROWSER

§ 07 — Launching in Florida

Physician-directed. In-clinic.

Signal is onboarding a limited cohort of licensed physicians for the initial rollout.

If you operate a longevity, neurology, or regenerative practice, request access below.

Physician intake

Or email clinics@signal.clinic